Ihre Suche
Ergebnisse 2 Einträge
-
OBJECTIVE: The quality of averaged gradient artifact subtraction from EEG recorded during fMRI is highly dependent on the accuracy of gradient artifact sampling. Even small sampling shifts (e.g. a single datapoint at 5kHz) increase the variance of the sampled gradient artifacts because of very steep slopes in the signal time course. Hence, although principally gradient artifacts are invariant signals because of their technical origin, variance attributed to sampling errors attenuates the effect of artifact removal. Recently, it has been shown that synchronizing the EEG-amplifier clock to the MR-scanner control-device clock improves artifact reduction by subtraction. METHODS: In order to investigate the synchronized measurement of combined EEG-fMRI, we used simulated EEG by measuring function generator signals in the MR-scanner. Only the usage of known signals allows an assessment of the improvement in accuracy of artifact recording by synchronized compared to non-synchronized measurement, since the signal is identical in both conditions. RESULTS: After averaged gradient artifact subtraction synchronized recorded signals were apparently less distorted than non-synchronized recorded signals. Spectral analyses revealed that especially artifact frequencies above 50Hz had less power in restored synchronized compared to restored non-synchronized recorded signals. Computed total signal variances were not always less in restored synchronized compared to restored non-synchronized recorded signals. CONCLUSIONS: Taken together, synchronizing simultaneous EEG-fMRI measurement is a useful enhancement for averaged gradient artifact subtraction although post-correction filtering is still necessary. SIGNIFICANCE: Our results support the recent finding that synchronization improves the quality of averaged gradient artifact subtraction. However, quantitatively we could not verify a systematic benefit of recording electrical signals during fMRI synchronously rather than non-synchronously to the MR-scanner control-device clock.
-
Event-related functional magnetic resonance imaging was applied to identify cortical areas involved in maintaining target information in working memory used for an upcoming grasping action. Participants had to grasp with their thumb and index finger of the dominant right hand three-dimensional objects of different size and orientation. Reaching-to-grasp movements were performed without visual feedback either immediately after object presentation or after a variable delay of 2-12 s. The right inferior parietal cortex demonstrated sustained neural activity throughout the delay, which overlapped with activity observed during encoding of the grasp target. Immediate and delayed grasping activated similar motor-related brain areas and showed no differential activity. The results suggest that the right inferior parietal cortex plays an important functional role in working memory maintenance of grasp-related information. Moreover, our findings confirm the assumption that brain areas engaged in maintaining information are also involved in encoding the same information, and thus extend previous findings on working memory function of the posterior parietal cortex in saccadic behavior to reach-to-grasp movements.
Erkunden
Team
- Vaitl (2)
Eintragsart
Sprache
- Englisch (2)
Thema
- Oxygen/blood
- Adult (1)
- Artifacts (1)
- Brain/*blood supply/*physiology (1)
- Brain Mapping (1)
- *Brain Mapping (1)
- Computer Simulation (1)
- *Cortical Synchronization (1)
- *Electroencephalography (1)
- Female (1)
- Hand Strength/*physiology (1)
- Humans (2)
- Image Processing, Computer-Assisted (1)
- Image Processing, Computer-Assisted/methods (1)
- Magnetic Resonance Imaging (1)
- Magnetic Resonance Imaging/*methods (1)
- Male (1)
- Memory, Short-Term/*physiology (1)
- Models, Biological (1)
- Motor Cortex/physiology (1)
- Orientation/physiology (1)
- Parietal Lobe/*physiology (1)
- Psychomotor Performance/*physiology (1)
- Somatosensory Cortex/physiology (1)
- Space Perception/*physiology (1)
- Spectrum Analysis (1)
- Supine Position/physiology (1)
- Time Factors (1)
- Visual Cortex/physiology (1)
- Visual Perception/physiology (1)
- Young Adult (1)