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Ergebnisse 2 Einträge
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This functional magnetic resonance imaging study investigated the disgust- and fear-reactivity of patients suffering from obsessive-compulsive disorder (OCD). Ten OCD patients were scanned while viewing blocks of pictures showing OCD triggers from their personal environment and OCD-irrelevant disgust-inducing, fear-inducing and neutral scenes. Afterwards, the patients rated the intensity of the induced disgust, fear and OCD symptoms. The responses were compared with those of 10 healthy control subjects. The disorder-relevant pictures provoked intense OCD symptoms in the clinical group associated with increased activation in the bilateral prefrontal cortex, the left insula, the right supramarginal gyrus, the left caudate nucleus and the right thalamus. The patients gave higher disgust and fear ratings than the controls for all aversive picture categories. Neural responses towards the disorder-irrelevant disgusting and fear-inducing material included more pronounced insula activation in patients than controls. Summarizing, photos of individual OCD-triggers are an effective means of symptom provocation and activation of the fronto-striato-thalamo-parietal network. The increased insular reactivity of OCD patients during all aversive picture conditions might mirror their susceptibility to experience negative somatic states.
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The aim of this fMRI study was to explore brain structures that are involved in the processing of erotic and disgust-inducing pictures. The stimuli were chosen to trigger approach and withdrawal tendencies, respectively. By adding sadomasochistic (SM) scenes to the design and examining 12 subjects with and 12 subjects without sadomasochistic preferences, we introduced a picture category that induced erotic pleasure in one sample and disgust in the other sample. Since we also presented neutral pictures, all subjects viewed pictures of four different categories: neutral, disgust-inducing, erotic, and SM erotic pictures. The analysis indicated that several brain structures are commonly involved in the processing of disgust-inducing and erotic pictures (occipital cortex, hippocampus, thalamus, and the amygdala). The ventral striatum was specifically activated when subjects saw highly sexually arousing pictures. This indicates the involvement of the human reward system during the processing of visual erotica.
Erkunden
Team
- Vaitl (2)
Eintragsart
Sprache
- Englisch (2)
Thema
- Hemodynamics/physiology
- Adult (2)
- *Affect (1)
- Amygdala/blood supply/metabolism (1)
- Anxiety/psychology (1)
- Basal Ganglia/blood supply/metabolism (1)
- Brain/*blood supply/metabolism (1)
- Cerebrovascular Circulation/physiology (1)
- Emotions/*physiology (1)
- *Erotica (1)
- Fear/*physiology (1)
- Female (2)
- Functional Laterality/physiology (1)
- Hippocampus/blood supply/metabolism (1)
- Humans (2)
- Magnetic Resonance Imaging (2)
- Male (2)
- Middle Aged (1)
- Obsessive-Compulsive Disorder/*physiopathology/psychology (1)
- Occipital Lobe/blood supply/metabolism (1)
- Personality (1)
- Personality Inventory (1)
- *Photic Stimulation (1)
- Photic Stimulation (1)
- Psychiatric Status Rating Scales (1)
- Reward (1)
- Sexual Behavior/physiology (1)
- Surveys and Questionnaires (1)
- Thalamus/blood supply/metabolism (1)